Climate change is among the most pressing conservation challenges of the twenty-first century because it has the potential to reconfigure the spatial distribution of species and their habitats. Development of predictive models of biological responses to climate change is key to responding to climate change impacts and developing fish and wildlife adaptation strategies. To meet the need for robust models of species response to climate change, our team is producing predictive models (climate envelope models) for 26 federally listed threatened and endangered species occurring in peninsular Florida. In addition to development of individual species models, we also are developing a flexible protocol for climate envelope modeling that is applicable to other species and geographic locations, and using a variety of media to place this information in the hands of natural resource managers. In this webinar, we will introduce participants to some of the decision support tools we are developing, present preliminary insights from species models, and outline a quantitative and spatially-explicit approach to describing uncertainty in climate envelope models.